Stem Cells - GCSE Biology

Introduction

  • Cells with the ability to divide repeatedly to produce more similar cells that also differentiate are called stem cells.
  • These are unspecialized, that is, they do not have a specific function.
  • They give rise to cells that specialize in different functions.
  • For example, stem cells develop into pancreatic cells and help in digesting sugar.
  • Another example, cells in the lungs are designed to exchange gases.

Real-life Examples

Educational diagram for showing examples of specialized cells: pancreatic cells, nerve cells, and lung cells.

Where are Stem Cells Found?

  • Stem cells are found in both plants and animals.
  • In plants, stem cells are present in meristems.
  • It includes the regions of apical meristem (root and shoot), lateral meristem (sides of stem and root), and intercalary meristem (base of leaves and internodes).
  • In animals, these cells are found in early-stage embryo and are called embryonic stem cells.
  • Apart from this, these can be observed in most adult tissues, known as adult stem cells.

What are the Functions of Stem Cells?

  • The major functions of stem cells are – Differentiation, tissue growth, and repair.
  • Stem Cells differentiate into specialized cells in both plants and animals.
  • After growth, they are found as adult stem cells that, in humans, allow tissue growth.
  • Cells that get old or are damaged need replacement. Stem cells replace these cells to repair the tissue.

Advantages of Using Stem Cells in Medicine

  • Diseases caused by damaged cells can be treated using stem cells.
  • Treatment of diseases such as type I diabetes. E.g., Bone marrow transplantation to cure a blood disease.
  • Study of stem cells can help appropriate drug development for humans.
  • With this, there is no need to test drugs on humans, as can be done in lab settings.
  • For example, testing on transparent young zebrafish.

Risk of Using Stem Cells In Medicine

  • Continued division after replacement of damaged cells can lead to cancer.
  • Using stem cells to treat a disease involves putting them in the body of the patient. The immune system of the body usually kills these cells.
  • The reason the immune system kills these cells is that they are treated as foreign particles.
  • It is known as rejection.

Function of Stem Cells in Bone Marrow

  • Stem cells are present in the middle of those bones in the body that are long, like the femur.
  • During their whole life, they divide continuously and produce new blood cells.
  • Stem cells can only give birth to those specialized cells that are in the tissue surrounding them.
  • Since blood stem cells are found in bone marrow and blood cells surround them, they produce blood cells only.

Diagram for Stem Cells GCSE showing adult stem cells in bone marrow differentiating into blood cells.

Comparison of Adult Stem Cells with Embryonic Stem Cells

  • Differences between Embryonic Stem Cells and Adult Stem Cells

Comparison table for Stem Cells GCSE detailing differences between Embryonic and Adult stem cells based on specialized cell production and function.

  • Stem Cells to Different Specialized Stem Cells that Develop into Organs

Diagram for Stem Cells GCSE showing embryonic stem cells differentiating into specialized organs like the heart, liver, and brain

  • Adult Stem Cells to Various Types of Blood Cells

Diagram illustrating how adult stem cells differentiate into red blood cells, white blood cells, and platelets.

Roles of Meristems in Plant Growth

  • In plants, the roots and shoots are the areas where growth happens.
  • Meristems are stem cells found in these regions.
  • The cells in meristems divide continuously by mitosis.
  • These take part in elongation as the length of the cells increases.
  • Refer to 7.Plant Meristem Elongation in Cell Differentiation & Specialization.

Frequently Asked Questions

Solution:

Stem cells are undifferentiated cells that undergo division to make more similar cells and differentiate into specialized ones.

Solution:

In animals, there are two types of stem cells. These include embryonic stem cells and adult stem cells.

Solution:

Stem cells are used for the treatment of diseases, replacement of damaged cells, and drug research.

Solution:

Usage of stem cells in medicine involves the risk of cancer and rejection by immune system.

Solution:

Adult stem cells are responsible for tissue growth and cell repair.